Challenging the absence of observable hydrogens in the assignment of absolute configurations by NMR: application to chiral primary alcohols.
نویسندگان
چکیده
The absolute configuration of beta-chiral primary alcohols devoid of observable hydrogens on one of the beta-substituents at the asymmetric carbon (L(1)/L(2)) can be determined by comparison of the (1)H NMR of their (R)- and (S)-9-AMA ester derivatives and analysis of the Deltadelta(RS) for the L substituent and the Cbeta-H.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 14 شماره
صفحات -
تاریخ انتشار 2007